This has offered hope for disease prevention and a healthier ageing process.
The lifespan-extending properties of phytoene
The research has revealed that the carotenoid phytoene increased the lifespan of Caenorhabditis elegans (a type of roundworm) by 10 to 18.6%. Phytoene is naturally found in food ingredients like;
- tomatoes,
- carrots,
- apricot and,
- red peppers.
The study focused on testing pure phytoene and extracts derived from microalgae, both of which showed significant benefits in greatly improving longevity.
This finding is important because Caenorhabditis elegans is a model organism frequently used in biomedical research. Its cellular mechanisms are similar to those of humans which makes it an excellent subject for ageing and disease studies.
Reducing alzheimer’s disease paralysis
It has also been discovered that phytoene lessens the paralysis caused on by Alzheimer’s. The study demonstrated a 30–40% reduction in the proteotoxic effects of amyloid plaques, which are linked to Alzheimer’s disease. The results offer an important advancement in the treatment of Alzheimer’s because these plaques usually cause neuron loss and paralysis in models of the illness.
While these are preliminary findings, the research team expressed optimism in determining the precise mechanisms behind phytoene’s protective benefits. This may open the door to new medications meant to slow the evolution of Alzheimer’s in people.
Role of phytoene in disease prevention
Because phytoene may have some health benefits, researchers have been examining it for a long time. Phytoene has been investigated for its ability to defend against UV radiation, in addition to its latest discoveries about ageing and Alzheimer’s disease. This carotenoid is found in many tissues, including the epidermis, and is well absorbed by the organism.